Publications
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Le XF, Pruefer F, Bast RC Jr. HER2-targeting Antibodies Modulatethe Cyclin-Dependent Kinase Inhibitor p27kip1 via Multiple Signaling Pathways. Cell Cycle. 2005 Jan 10;4(1)
Franz G Pruefer , Karla Unger Saldaña , Vilma Maldonado-Lagunas V,
Jorge Meléndez-Zajgla J. Hepatocyte Growth Factor lacks prognostic significance
in Mexican breast cancer patients. Journal of Experimental and
Clinical Cancer Research 2006 Sep;25(3):357-64
Franz G Pruefer , Lizárraga-Sánchez F, Maldonado-Lagunas V, Meléndez-
Zajgla J. Participation of Omi Htra2 serine-protease activity in the apoptosis induced by
cisplatin on SW480 colon cancer cells . Journal of Chemotherapy 2008 June; 20(3)348-54
Clempner J, Franz G Pruefer , Carsteanu A. DPPN for Modeling BiologicalNetworks. (Manuscript Submitted)
Franz G Pruefer, Carsteanu A, Clempner J. Modeling HER2 signal transduction after treatment with
HER2-monoclonal antibody on Breast Cancer Cells through Games theory,Prisoners dilemma.
(Manuscript Submitted)Lectures
Principal instructor at the theoretical and practical course of Bioinformatics Tools. (16 hours, Nov 28th-Jan10th 2006) Mexican National Cancer Insitute. Mexico City
Apoptosis in Cancer “Implications in Pathophysiology and Future Treatments” Lectures to Medical Oncology Residents at the Mexican National Cancer Insitute. April 2005. Mexico City.
Oral Presentations
Modeling of Biological Networks using Decision Process Petri Nets. International Practical and Theoretical Course on Genomic Proteomics and Bioinformatics. Organized by European Molecular Biology Organization / International Cell Research Organization/ International Union of Biochemistry and Molecular Biology. October 2005 in Santiago de Chile
Apoptosis Inducida por CDDP pero no por 5-FU en células de cáncer de colon depende de Omi/Htra2. 60th Anniversary of the Mexican National Cancer Institute. February 2007. Mexico City
Omi/Htra2rA2 and Apoptosis in Colon Cancer. Medical Social Service in Research Meeting. Secretaria de Salud (Mexican Ministry of Health). August 2004. Mexico City
Poster Presentations
Centrosome disruption suppresses Multipolar Spindle Formation on Polyploid cells.
Franz Pruefer, Jasmine Zhou, Roy Wollman, Ron Vale, Gohta Goshima.
Presented at: Annual Meeting American Society for Cell Biology Dec 2006
Live cell imaging of interactions between hematopoietic progenitor cells and osteoblastic cells.
Jenniffer Gillette, Franz Pruefer, Jasmine Zhou, Jennifer Lippincott Schwartz
Presented at: Annual Meeting American Society for Cell Biology Dec 2006
This presentation was cited on, News Guides US, Stem cells news, & News from Eureka Alert
Apoptosis induced by Cisplatin but not by 5-FU depends on Omi serine-protease activity in SW480 Colon Cancer Cells.
Presented at:
1) Mouse Models of Cancer: American Association for Cancer Research. Oct 25-28, 2006: Cambridge MA
2) International Practical and Theoretical Course on Genomics Proteomics and Bioinformatics. European Molecular Biology Organization (October 2005 in Santiago de Chile)
3) International Oncology Congress. Sociedad Mexicana de Oncología, ITESM. 2006 Monterrey Mexico.
Cervical Cancer in Mexico. Presented at “Oncology for Medical Students 2000”. Organized by the World Health Organization, Collaborating Centre for Cancer Education. AZG. July 2000 Groningen, Netherlands.
Review of the Role of NGF (Nerve Growth Factor) in Diverse Pathologies. III National Scientific Meeting of Medical Students of Mexico. Mexico City, 1999.
Franz Pruefer